Very Good 1772 Reviews
Jetsetter Approved
This Hotel meets our standards
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  •  Free WiFi
  •  Gym
  •  Handicap-accessible
  •  Parking On Site
  •  Pool
  •  Restaurant
  •  Spa
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grass property Garden cottage Courtyard Villa yard outdoor structure backyard hacienda Village plant stone



Located in Antigua Guatemala, Hotel Museo Spa Casa Santo Domingo is minutes from Jade Maya Factory and Museum and Las Capuchinas Convent. This 4-star hotel is within close proximity of Choco Museum and Santa Clara Convent.


Treat yourself to a stay in one of the 130 guestrooms, featuring fireplaces and LCD televisions. Complimentary wireless Internet access keeps you connected, and cable programming is available for your entertainment. Conveniences include phones, as well as safes and complimentary newspapers.

Spa, Wellness & Premium Amenities

Pamper yourself with a visit to the spa, which offers massages, body treatments, and facials. You can take advantage of recreational amenities such as a health club, an outdoor pool, and a sauna. This hotel also features complimentary wireless Internet access, concierge services, and a hair salon.

Food & Drink

Grab a bite at one of the hotel’s 2 restaurants, or stay in and take advantage of 24-hour room service. Relax with a refreshing drink from a poolside bar or one of the 2 bars/lounges. Full breakfasts are available daily from 6 AM to 11 AM for a fee.

Business & Travel Amenities

Featured amenities include a business center, express check-out, and complimentary newspapers in the lobby. Event facilities at this hotel consist of conference space and meeting rooms. A roundtrip airport shuttle is provided for a surcharge (available 24 hours).

How to Get There

Hotel Museo Spa Casa Santo Domingo
3a Calle Oriente No 28 A
Antigua Guatemala, 03001 Guatemala


4.5 Very Good 1772 Reviews
Heaven on Earth
Reviewed 5 days ago

Amazing! Beautiful stay. It’s really a peace of heaven on Earth. Love every second of our stay. Friendly personnel. I will definitely recommend this hotel. Go to the SPA and have a relaxing pampered day. Food is good and breakfast was excellent. Wish it could be included in the price of the room.

5 Star Hotel and SPA
Reviewed 6 days ago

A really amazing hotel!! The staff is friendly and courteous, always willing to go the extra mile to help you. The breakfast buffet on Sundays is out of this world. Cooked to order egg perfection. Loved the pool and SPA area as well.

Amazing stay as usual
Reviewed 7 days ago

We have been staying at the famous Casa Santo Domingo pretty much since it opened for business when I was a kid. I've watched it grow and become the icon of Antigua and Guatemala it is now. Everything was amazing as usual, the room, staff and facilities. But what really stood out this last stay was the high culinary level of Chef Mario Campollo and the incredibly relaxing new Spa. I got a great massage, enjoyed the Turkish bath pools, saunas and had a healthy breakfast at the new spa restaurant. Highly recommended for a day of relaxation! Great job, keet it up!

Lovely hotel
Reviewed 2 weeks ago

Had a very nice stay here. The rooms were clean, the staff was friendly, the grounds were interesting and well cared for, the food was good and my husband loved the fresh hot coffee the hotel put out every morning in the hallway.

Lunch @ the hotel
Reviewed 2 weeks ago

Beautiful grounds with many things to visit like a chocolaterie and little stores, it was a monastery so it is nice to walk around. They have beautiful parrots around the hotel too.
The pool looked very nice, we went for a catering event and the food was excellent!