Very Good 2042 Reviews
Jetsetter Approved
This Hotel meets our standards
This hotel meets our standards, but we haven't stayed yet


  •  Free WiFi
  •  Gym
  •  Handicap Accessible
  •  Parking On Site
  •  Pool
  •  Restaurant
  •  Spa
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grass property Garden cottage Courtyard Villa yard outdoor structure backyard hacienda Village plant stone



Located in Antigua Guatemala, Hotel Museo Spa Casa Santo Domingo is minutes from Jade Maya Factory and Museum and Las Capuchinas Convent. This 4-star hotel is within close proximity of Choco Museum and Santa Clara Convent.


Treat yourself to a stay in one of the 130 guestrooms, featuring fireplaces and LCD televisions. Complimentary wireless Internet access keeps you connected, and cable programming is available for your entertainment. Conveniences include phones, as well as safes and complimentary newspapers.

Spa, Wellness & Premium Amenities

Pamper yourself with a visit to the spa, which offers massages, body treatments, and facials. You can take advantage of recreational amenities such as a health club, an outdoor pool, and a sauna. This hotel also features complimentary wireless Internet access, concierge services, and a hair salon.

Food & Drink

Grab a bite at one of the hotel’s 2 restaurants, or stay in and take advantage of 24-hour room service. Relax with a refreshing drink from a poolside bar or one of the 2 bars/lounges. Full breakfasts are available daily from 6 AM to 11 AM for a fee.

Business & Travel Amenities

Featured amenities include a business center, express check-out, and complimentary newspapers in the lobby. Event facilities at this hotel consist of conference space and meeting rooms. A roundtrip airport shuttle is provided for a surcharge (available 24 hours).

How to Get There

Hotel Museo Spa Casa Santo Domingo
3a Calle Oriente No 28 A
Antigua Guatemala, 03001 Guatemala


4.5 Very Good 2042 Reviews
Magical hotel!
Reviewed 1 day ago

The hotel is magical and serene, taking you back in time. Our room was lovely, quiet, with a fireplace and small balcony. The hallways and walkways are enchanting with artwork and fountains throughout. The museums on the grounds were interesting and not crowded at all. The service was also outstanding. When we return to Antigua - we will definitely stay at Casa Santo Domingo again.

Why would you choose any other Hotel?
Reviewed 3 days ago

We have been in Guatemala approximately five or six times. We've always stayed at different hotels or houses Missy letter to my spouse's dismay. When we arrived at this hotel, we were amazed. Why would we have stayed at any other location in Antigua Guatemala question mark the service was impeccable. And Four Knights here I did not pass by someone who did not greet us okay buenos dias. They have a candle and ceramic shop on site where we had classes for our children with portable souvenirs. The restaurants we're delicious and ever accommodating. The pool and jacuzzis were warm and set against a beautiful backdrop. Most notably, the beds were extremely comfortable and extremely clean. We are so happy with our stay here and will never seek out another hotel on any return visits.

Perfect place to relax
Reviewed 2 weeks ago

Stayed at one of the SPA section room and was amazing. Despite the fact that it was a busy weekend (national holiday in Guatemala) the SPA atmosphere was quiet and very calm. The food at the SPA restaurant was amazing and the deep tissue massage I got was excellent as well.
Not my first time at this hotel and I keep coming back. Totally worth it!

Magical Place
Reviewed 2 weeks ago

What a magical place! They keep it very nice, but it seems like you've stepped back in time 200-300 years as you enter this property. It's a huge property, complete with ruins, an amazing restaurant (maybe the best in Antigua?), amazing views, gardens. The rooms were really nice, clean & seeming new, yet hundreds of years old!

I really hope to return here again.

Santo Domingo
Reviewed 3 weeks ago

Excellent service with beautiful gardens and museums if you are staying as a guest you have direct access to the Museums inside the hotel, this is an upscale spot so be prepared to spend $$$$, we stayed in a beautiful suite with private jacuzzi and beautiful view to magnificent garden, the restaurant offers great variety and the food was simply delicious, 💘