Very Good 1492 Reviews
Jetsetter Verified
This Hotel meets our standards
Our editors have been here and it has met our standards

What We Love

  • Chef Michael Paley’s seasonal, wood-fired menu at the house restaurant, Metropole
  • The free contemporary art gallery, open 24 hours a day, 7 days a week
  • A nine-story airshaft repurposed as an iridescent fiber optic exhibit by Danish artist Astrid Krogh

What To Know

  • The gym is open 24 hours and there is a full-service spa on the 11th floor
  • Some contemporary art exhibits aren’t for the tenderhearted
  • Overnight valet parking (with in-and-out privileges) is available for $28 per night
  • Free WiFi


  •  Bar
  •  Eco friendly
  •  Free WiFi
  •  Gym
  •  Handicap-accessible
  •  Parking On Site
  •  Pet-friendly
  •  Restaurant
  •  Spa
Disclaimer: This content was accurate at the time the hotel was reviewed. Please check our partner sites when booking to verify that details are still correct.
Bedroom Boutique Food + Drink Lounge Modern property Suite home living room cottage condominium


Mod, art-centric boutique hotel, with a 24-hour art gallery, tony restaurant and rooftop bar in downtown Cincinnati

The Look

The 21c is an artful blend of turn-of-the-last-century architecture and a contemporary disposition. The building is listed on the National Register of Historic Places, and owners Laura Lee Brown and Steve Wilson — who kicked off the concept with their flagship Louisville location — worked with architect Deborah Berke to preserve its vintage appeal while integrating a contemporary interior overhaul. It’s hard to miss the elaborate mosaic tile floor and terra-cotta and plaster molding details. Browse the striking mixed media exhibits in the 8,000-square-foot gallery space, and then enjoy more original art in each guestroom. No generic sofa paintings here.

Bed and Bath

Guestrooms are a balance of chic and cozy, pairing modish furnishings with supersoft linens, plus handy amenities like iPod docks and Nespresso coffeemakers. Suites sport two flat-screen televisions and an impressive walk-in wet room with steam shower and tub (rubber duck included), elegant black-and-white decor and lovely Malin + Goetz bath products (you’ll want to pinch the cilantro hair conditioner).


Nearly every dish on chef Michael Paley’s inventive menu takes a spin in Metropole’s custom-built wood-burning oven, and he changes up the offerings regularly — though the string-roasted chicken is (so far) a reliable local favorite. Stop in for a light breakfast of wheatberry granola, or lunch on the charred spicy mortadella sandwich. After hours the bar turns out a mean Old Fashioned (dubbed the Don and Dirty in an homage to Mad Men’s rye-swilling Don Draper). But don’t miss the menu of shrubs, tasty colonial-era cocktails laced with flavored vinegar and such seasonal ingredients as Concord grape with juniper, or carrot with basil and achiote.

In the Area

The 21c is located smack in the middle of this compact city. See more art next door at the Contemporary Arts Center, and walk two blocks northwest to Jean-Robert de Cavel’s French Crust Café for an almond croissant or dejeuner of beef short rib with red potatoes and mushrooms. Don’t miss wandering over to Over-the-Rhine, a revitalized Italianate neighborhood just blocks from downtown, where you can try Senate’s gourmet hot dog, Abigail Street’s creamy bouillabaisse, or Bakersfield’s street cart–style tacos. And a must-see spot is Findlay Market, Ohio’s oldest continuously operated public market and home to dozens of year-round grocery, craft and carry-out food vendors.

How to Get There

21c Museum Hotel Cincinnati
609 Walnut St
Cincinnati, OH 45202 United States


4.5 Very Good 1492 Reviews
Reviewed 6 days ago

This hotel provides a great stay as well as a great experience. The excellent service and attention to detail is evident from the minute you pull up to the 21C Hotel.... plus the yellow penguins who appear randomly and the art through out the hotel make the stay special. 5 STARS

Love Contemporary Art in Downtown Cincy
Reviewed 6 days ago

Great hotel!! The rooms are clean, well designed and the art spectacular. The front desk staff were friendly, accommodating and well informed. I am looking forward to a weekend trip to Cincy for fun and I will be staying at the 21c.

The Future is Female at 21C Cincinnati
Reviewed 1 week ago

For the second time in as many years, I found myself in Cincinnati and visiting another great exhibition in one of the South’s most inspiring and original Hotels, 21C.

Situated in the heart of downtown Cincinnati, 21C Museum Hotel is a boutique Hotel and Museum all in one. It doesn’t just have art as décor, it has a complete, properly curated museum with cutting edge 21st century works.

Showing until September, the present exhibition, The Future is Female, includes some of the most thought provoking, creative, reflective language and works by both global and US artists such as Stephanie Hirsch (a personal favorite), Alison Saar, Lesley Dill and Gaela Erwin.

Should you be traveling in the Mid-South, and stopping in Cincinnati this summer, I highly encourage you to “experience” 21C Museum Hotel and this current exhibition, The Future is Female.

I am happy to share more on my blog @mcsartofliving ...I hope it will inspire you to explore and find your own Art of Living.

Cheers, MC

Fun Place To Stay
Reviewed 1 week ago

Great location, great staff, very accommodating! Staff is helpful in recommending places to eat and how to get around. Take the art tour. Knowledgeable docent. Interesting old building. Breakfast could be more creative. The place to stay when you are in Cincinnati.

Treat Yourself Weekend
Reviewed 2 weeks ago

Great hotel and spa service were on point. Spa was amazing experience. Room service is directly from posh restaurant attached-great food and reasonably priced.
The staff went above and beyond. I’m not one to usually say so, but they did. I fell ill and they went to store on my behalf.
Close to everything in a safe walking environment.