Very Good 617 Reviews
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What We Love

  • An artistic stay at a unique new property that's part boutique hotel, part art museumThe intriguing and even provocative artwork hanging or standing throughout the property
  • The brand-new hotel itself, located in a historic sksycraper by McKim, Mead & White
  • The location in downtown Lexington, whose cultural scene is on the rise

What To Know

  • Opened in February 2016
  • Lockbox restaurant serves up seasonal, locavore dishes
  • The brand-new property is still perfecting its service; there may be some staff hiccups in the meantime
bathroom property sink mirror Kitchen home countertop cabinetry flooring


A spacious room or suite at a brand-new boutique hotel with its own contemporary art museum

The Lowdown

21c Museum Hotel Lexington has refined hospitality to an art – or rather, lots of it. A perfect addition to its city, which houses a slew of galleries and a renowned ballet company, this brand-new stay is both a boutique hotel and a contemporary gallery itself. Contemporary art appoints every room or public space; it’s as cutting-edge as what you’ll find in cities like Louisville and Cincinnati, whose 21c hotels have fast become TripAdvisor and Condé Nast Traveler favorites.
The collection is curated by a seasoned art-world pro, but it got its sharp redesign by high-profile Deborah Berke Partners. Before that, it was a bank, in a 1914 skyscraper (Lexington’s first) by McKim, Mead & White – the architects behind the Columbia University campus. Old-fashioned details still abound here, and you’ll see them as you explore. Swing by Lockbox restaurant, which retains some of its original marble and plasterwork, and realize you’re not just among works of art – you’re in one.

Rooms and suites

 Your 21c abode is well-stocked, with a sleek Nespresso coffee machine, a 43-in. flat-screen HDTV and bath amenities by MALIN + GOETZ. But all this is secondary to the real star of the show – the original artwork sharing the space. Choose between a spacious Corner King room of 427 square feet, with lots of natural light from windows with two exposures, and a 686-square-foot, one-bedroom Deluxe suite, which also holds a living and dining area, a double vanity and a second TV. 


 Lockbox serves dinner and dessert under the direction of Executive Chef Jonathan Searle, drawing from the flavors and ingredients of surrounding Kentucky. Menus are seasonal, but a sample meal might feature Kentucky silver catp with toasted farro or a roasted-cauliflower soup with brown butter. Dessert options include the olive-oil cake with blood-orange curd and pistachio ice cream, with select liquors and wines available for pairings.It all happens in a space as sleek and sharp as the rest of the hotel, designed by award-winning Deborah Berke Partners, with original marble flooring and decorative plaster from its origins as Lexington’s first skyscraper. And yes, there are art exhibitions on rotation here, too. 


 Downtown Lexington is on the rise (not least because of this hotel), but its evolving cultural scene stands on a solid foundation. This city has offered a variety of dance-related offerings, musical acts and modern-art galleries for years, and there’s some impressive street art to see, as well. Of course, it’s horses that are Lexington’s most famous draw, so make sure to learn about them at Keeneland Race Course, depending on the season, or the popular museum dedicated to the native American Saddlebred. Other highlights include sprawling estates and historic sites in the area, such as Mary Todd Lincoln’s childhood home.

How to Get There

21c Museum Hotel Lexington
167 W Main St
Lexington, KY 40507 United States


4.5 Very Good 617 Reviews
Lovely couples getaway
Reviewed 6 days ago

My husband and I had a lovely stay on our way back from dropping our daughter off at a camp in Ohio. Since we haven't been away from our kids in 19 years, we decided to stay somewhere interesting. This definitely was a lovely place to get away. The staff was friendly and helpful. The hotel was clean and beautifully decorated. The room was beautiful and our view of Lexington was great. There were lots of little touches that made it so nice...master light switches on the headboard, a couch, extra blanket in the bathroom, heated tile floors in the bathroom, bathrobes, etc. The museum was an interesting place to go after a late dinner and a long drive.

Fantastic accommodations and attentive staff
Reviewed 6 days ago

We stayed at the hotel to ride the local bike trail. The staff was very accommodating of our bikes and the storage of our baggage until the rooms were ready. Our corner Kings were gorgeous, large and full of light with large sets of windows on two walls. We asked for a late checkout and it was granted. I took a fab yoga class in the middle of the main gallery. Then brunch was perfect. Kudos to all!!!

Great please to stay in Lexington
Reviewed 7 days ago

I truly enjoyed my stay at 21c Museum Hotel/Lexington. The employees were very friendly and professional, the rooms are beautifully decorated, the common areas are very clean, the food at the restaurant was awesome, and the art gallery to fantastic.

Lovely hotel!
Reviewed 7 days ago

Lovely hotel - very eclectic which made the stay all the better. Staff were wonderful from the room staff to the bell hop and front desk. Location is perfect to walk anywhere including UK campus if your up for a walk!

Best Night in a Long Time
Reviewed 1 week ago

From check-in to check-out was a great experience. Will for sure stay here on my next pass through town. It will not disappoint. Having the opportunity to walk through the art galleries and clear my mind after travel and work was so great. Dining room menu offered great choices. Room service for breakfast was right on time. Staff friendly and knowledgeable. This place was spot on!.