Very Good 3078 Reviews
Jetsetter Approved
This Hotel meets our standards
This hotel meets our standards, but we haven't stayed yet

What To Know

  • Within walking distance of Union Square, Chinatown, and North Beach
  • Free coffee can be found in the lobby each morning and free wine receptions are held at night
  • WiFi comes at an extra cost


  •  Bar
  •  Gym
  •  Handicap-accessible
  •  Parking On Site
  •  Pet-friendly
  •  Restaurant
  •  Spa
Disclaimer: This content was accurate at the time the hotel was reviewed. Please check our partner sites when booking to verify that details are still correct.
property Lobby living room Suite conference hall recreation room function hall



Serrano Hotel is centrally located in San Francisco, walking distance from Powell and Market Cable Car Turnaround and close to Asian Art Museum of San Francisco. This 4-star hotel is within close proximity of San Francisco Museum of Modern Art and Cable Car Museum.


Make yourself at home in one of the 236 air-conditioned rooms featuring flat-screen televisions. Pay movies and video-game consoles are provided for your entertainment, while wireless Internet access (surcharge) keeps you connected. Private bathrooms with shower/tub combinations feature designer toiletries and hair dryers. Conveniences include phones, as well as laptop-compatible safes and desks.

Spa, Wellness & Premium Amenities

Take advantage of recreation opportunities such as a 24-hour fitness center, or other amenities including wireless Internet access (surcharge) and concierge services.

Food & Drink

Enjoy a satisfying meal at a restaurant serving guests of Serrano Hotel. Quench your thirst with your favorite drink at a bar/lounge. Breakfast is available for a fee.

Business & Travel Amenities

Featured amenities include a 24-hour business center, dry cleaning/laundry services, and a 24-hour front desk. Planning an event in San Francisco? This hotel has 3000 square feet (279 square meters) of space consisting of conference space and a meeting room.

How to Get There

Serrano Hotel
405 Taylor St
San Francisco, CA 94102 United States


4.0 Very Good 3078 Reviews
Lovely hotel
Reviewed 3 days ago

We had a great time staying at Hotel Spero earlier this month (May).

Our room was well appointed, spacious enough and extremely clean.

We opted out of daily housekeeping in exchange for a Jaspers credit voucher, which is a good idea. Had breakfast and an evening snack at Jaspers, as well as a few drinks, all of which were really good.

Having read some negative reviews about the location I was slightly nervous about our stay but we didn't find the location a problem at all and wouldn't hesitate to stay here again.

Daily coffee served in the main reception area of the hotel in the mornings is a great touch and was much appreciated when dealing with jet lag!

We didn't have many dealings with staff but when we did they were helpful, friendly and efficient.

Overall, we had a great stay and would definitely recommend to others.

Old, dirty building with the facade that it’s been updated
Reviewed 3 days ago

Got to the hotel at check in and we’re told our room wasn’t ready yet.

They then upgraded us to a king since they screwed up our room which was nice, but they put us as close to the elevator as physically possible. Little did I know this hotel has paper thin walls. Clearly not considered during the renovations. We were woken up all night long by the elevator and people just standing outside our room talking quietly. By the way the elevator feels like it will collapse at any minute and it clanks the whole way down. Our bathtub was filthy, the thermostat didn’t work.

When we requested a new room, again we were told nothing was ready and we would need to wait all day for a new room, and to come back later in the day and they might have something. Not a good customer experience in any way. It’s a Monday in San Fran and the hotel had rooms available... why couldn’t we just get moved. Unbelievable

Hotel Spero for the WIN!
Reviewed 5 days ago


Wow, who ever updated your hotel is a damn genius.

The smells, colors, decor! LOVE. There are design elements that play to some many senses. I love the mix of nature, minimalism and the splash of color.

The staff is superb, I really felt at home. They went out of their way to make me fell comfortable. I even got a cool water bottle, and a courtesy call in the morning. Your team is great!

Book this hotel, you will not regret!

Reviewed 6 days ago

Hotel Spero was the perfect location for our trip. Hotel staff provided us with whatever we needed. Jaspers food is delicious. Our room was spotless and very comfortable! Shopping, site seeing, restaurants of all kinds all within walking distance. Staying at Hotel Spero was a wonderful experience, I strongly recommend it!

Giant's Game
Reviewed 6 days ago

Came to S.F. for a Giant's game...Your Hotel, staff and the view from our 10th floor room was great.
Thanks, for making our one night stay memorable. Jasper's was very nice, food was awesome and the wait staff was pleasant and accommodating.